BioEngineering Research Group
Thoracoabdominal aortic aneurysms
To Develop An Advanced Patient Specific Computational Test-bed for the Evaluation Of Aortic Endografts In The Treatment Of TAAAs
Thoracic Aortic Aneurysms (TAAs) although less common than Abdominal Aortic Aneurysms (AAAs) are believed to rupture more frequently, with 95% of patients asymptomatic until the catastrophic point of rupture. With an associated mortality rate following aortic rupture of over 90%, aneurysms affecting the ThoracoAbdominal Aorta therefore, present a daunting challenge to vascular surgeons and interventionalists worldwide in optimizing treatment for these unpredictable aneurysms.
Currently the threshold for intervention for such aneurysms rests at a diameter of 5.5 cm orthogonal to the aortic centerline, however this threshold has been generated from investigations into the rupture risk of AAAs and does not account for the innate biomechanical differences between the thoracic and abdominal aorta. Investigation into the tissue biomechanics of ThoracoAbdominal Aortic Aneurysms (TAAAs) will allow for a greater understanding of localized disease progression and subsequently more accurate timing of surgical interventions.
For more information on this research project, contact Jamie Concannon.
Stanford Type B aortic dissection
For more information on this research project, contact Brian FitzGibbon.
Aortic arch dissection
Hemodynamic Study of Complex Aortic Arch Aneurysms after Endovascular Repair
For more information on this research project, contact Ala Elhelali